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\u53c2\u8003\u6587\u732e<\/strong><\/p>\n\n\n\n

  1. Wu PK, et al<\/em>. Mortalin (HSPA9) facilitates BRAF<\/em>-mutant tumor cell survival by suppressing ANT3-mediated mitochondrial membrane permeability. Sci Signal, 13: eaay1478, 2020.<\/li>
  2. Wu PK, et al<\/em>. Mortalin\/HSPA9 targeting selectively induces KRAS tumor cell death by perturbing mitochondrial membrane permeability. Oncogene, 9: 4257-70, 2020.<\/li>
  3. Srivastava S, et al<\/em>. Evolving paradigms on the interplay of mitochondrial Hsp70 chaperone system in cell survival and senescence.<\/a> Crit Rev Biochem Mol Biol, 54: 517-36, 2019.<\/li><\/ol>\n\n\n\n

    \u7528\u8a9e\u89e3\u8aac<\/p>\n\n\n\n

    * ANT3\uff08\u30a2\u30c7\u30cb\u30f3\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u30c8\u30e9\u30f3\u30b9\u30ed\u30ab\u30fc\u30bc3 )\uff1a\u30a2\u30c7\u30cb\u30f3\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u4ea4\u63db\u8f38\u9001\u4f53.\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306e\u8f38\u9001\u7cfb\uff0cATP-ADP\u8f38\u9001\u4f53\u3067\uff0cAAA\uff08ATP:ADP Antiporter\uff09\u3068\u3082\u547c\u3070\u308c\u308b\uff0eANT3\u306f\uff0cmPTP\uff08mitochondrial permeability transition pore\uff0c\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u900f\u904e\u6027\u9077\u79fb\u5b54\uff09\u3092\u69cb\u6210\u3057\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u308b\uff0e<\/p>\n\n\n\n

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