\u4e00\u793e\uff09\u65e5\u672c\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\u5b66\u4f1a\u30cb\u30e5\u30fc\u30b9No.111\u3010\u5b66\u8853\u5831\u544a46\u3011
\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\u306b\u95a2\u3059\u308b\u6700\u8fd1\u306e\u8a71\u984c46<\/p>\n\n\n\n
\u201c\u30aa\u30f3\u30b3\u30b5\u30fc\u30df\u30a2\u201d\uff08Modulated Electro Hyperthermia [mEHT])\u306e\u81e8\u5e8a\u5fdc\u7528\u306b\u95a2\u3059\u308b\u6700\u8fd1\u306e\u77e5\u898b\u306b\u3064\u3044\u3066<\/strong><\/p>\n\n\n\n \u5897\u6c38\u3000\u614e\u4e00\u90ce\uff08\u4eac\u90fd\u5927\u5b66\u8907\u5408\u539f\u5b50\u529b\u79d1\u5b66\u7814\u7a76\u6240, \u653e\u5c04\u7dda\u751f\u547d\u79d1\u5b66\u7814\u7a76\u90e8\u9580, \u7c92\u5b50\u7dda\u751f\u7269\u5b66\u7814\u7a76\u5206\u91ce\uff09<\/p>\n\n\n\n \u4e00\u822c\u306b43\u00b0C\u3092\u8d85\u3048\u308b\u30cf\u30a4\u30d1\u30fc\u30b5\u30df\u30a2\u306f\u5358\u72ec\u3067\u3082\u6297\u816b\u760d\u52b9\u679c\u3092\u793a\u3059\u304c\uff0c\u816b\u760d\u7d30\u80de\u306e\u64ad\u7a2e\u3092\u52a9\u9577\u3059\u308b\u53ef\u80fd\u6027\u306e\u3042\u308b\u5468\u56f2\u7d44\u7e54\u3078\u306e\u8840\u6d41\u306e\u5897\u52a0\u306a\u3069\uff0c\u6f5c\u5728\u7684\u306a\u30ea\u30b9\u30af\u3082\u3042\u308b\uff0e\u307e\u305f\uff0c\u816b\u760d\u5185\u306e\u8840\u6d41\u304c\u5236\u9650\u3055\u308c\uff0c\u816b\u760d\u3078\u306e\u85ac\u7269\u9001\u9054\u304c\u6e1b\u5c11\u3059\u308b\u53ef\u80fd\u6027\u3082\u3042\u308b\uff0e\u52a0\u3048\u3066\uff0c\u5927\u304d\u306a\u816b\u760d\u30b5\u30a4\u30ba\u3084\u58ca\u6b7b\u7d44\u7e54\u7b49\u306e\u4e0d\u5747\u4e00\u306a\u7d44\u7e54\u7279\u6027\u306e\u305f\u3081\u306b\uff0c\u816b\u760d\u5185\u6e29\u5ea6\u306f37\u00b0C\u304b\u308943\u00b0C\u4ee5\u4e0a\u307e\u3067\u5909\u5316\u3057\uff0c\u76ee\u7684\u90e8\u4f4d\u3092\u4e00\u5b9a\u306e\u6e29\u5ea6\u306b\uff0c\u304b\u3064\u5747\u4e00\u306b\u52a0\u71b1\u3059\u308b\u3053\u3068\u306f\u56f0\u96e3\u3068\u3055\u308c\u308b\uff0e<\/p>\n\n\n\n \u201c\u30aa\u30f3\u30b3\u30b5\u30fc\u30df\u30a2\u201d\uff08Modulated Electro Hyperthermia (\u4ee5\u4e0bmEHT\uff09)\u306f\uff0cAndras Szasz\u6559\u6388\u306b\u3088\u3063\u3066\u63d0\u6848\u3055\u308c\u305f\u6bd4\u8f03\u7684\u65b0\u3057\u3044\u52a0\u6e29\u624b\u6cd5\u3067\u3042\u308b\uff0e\u5f93\u6765\u306e\u52a0\u71b1\u65b9\u6cd5\u3068\u306f\u7570\u306a\u308a\uff0c\u5747\u4e00\u306a\u6e29\u5ea6\u5206\u5e03\u3092\u76ee\u6307\u3059\u3082\u306e\u3067\u306f\u306a\u304f\uff0c\u60aa\u6027\u816b\u760d\u306e\u7d30\u80de\u5916\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u3068\u7d30\u80de\u819c\uff0c\u7279\u306b\u30bf\u30f3\u30d1\u30af\u8cea\u30af\u30e9\u30b9\u30bf\u30fc\uff08\u751f\u4f53\u819c\u30e9\u30d5\u30c8\u69cb\u9020\uff09\u304c\u9078\u629e\u7684\u306b\u52a0\u6e29\u3055\u308c\u308b\u3068\u8aac\u660e\u3057\u3066\u3044\u308b1)<\/sup><\/strong>\uff0e\u3053\u3053\u3067\u306f\uff0c\u6700\u8fd1\u5831\u544a\u3055\u308c\u305fmEHT\u306b\u95a2\u3059\u308b\u81e8\u5e8a\u77e5\u898b\u3092\u96c6\u3081\u305f\u7dcf\u8aac\u306b\u3064\u3044\u3066\u7d39\u4ecb\u3059\u308b\uff0eSzasz AM\u3089\u306b\u3088\u308b\u7dcf\u8aac2)<\/sup><\/strong>\u3067\u306f\uff0c\u521d\u3081\u306bmEHT\u304c\u8840\u6d41\u8abf\u7bc0\uff0c\u816b\u760d\u7d30\u80de\u306e\u9078\u629e\u7684\u52a0\u6e29\uff0c\u7d30\u80de\u9593\u7d50\u5408\u306e\u518d\u7de8\u6210\uff08re-establishing cellular connections\uff09\u306b\u5f71\u97ff\u3057\uff0c\u305d\u306e\u5f8c\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u3084\u514d\u75ab\u539f\u6027\u7d30\u80de\u6b7b\u306e\u8a98\u5c0e\uff0c\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u3084\u30a2\u30d6\u30b9\u30b3\u30d1\u30eb\u52b9\u679c\u7b49\u306b\u5230\u308b\u904e\u7a0b\u3092\u8aac\u660e\u3057\u3066\u3044\u308b\uff0e\u6b21\u306bmEHT\u306e\u5b89\u5168\u6027\uff0c\u5b50\u5bae\u9838\u764c\uff0c\u8133\u816b\u760d\uff0c\u8179\u819c\u8ee2\u79fb\u306e\u81e8\u5e8a\u4f8b\u3092\u307e\u3068\u3081\uff0c\u500b\u5225\u75c7\u4f8b\u306e\u5831\u544a\u3082\u793a\u3057\u305f\uff0e\u7279\u306b\u8102\u80aa\u5c64\u306e\u539a\u3055\u306b\u3088\u3089\u305a\u6df1\u90e8\u52a0\u6e29\u3067\u304d\u308b\u70b9\uff0c\u3044\u308f\u3086\u308b\u30de\u30a4\u30eb\u30c9\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\u6e29\u5ea6\u3067\u816b\u760d\u8840\u6d41\u306e\u6539\u5584\u3084\u85ac\u5264\u5438\u53ce\u306e\u5411\u4e0a\u304c\u898b\u8fbc\u307e\u308c\u5897\u611f\u624b\u6cd5\u3068\u3057\u3066\u306e\u6709\u7528\u6027\u3092\u8ff0\u3079\u3066\u3044\u308b\uff0e\u6e29\u71b1\u7642\u6cd5\u306e\u8ffd\u52a0\u306b\u3088\u308b\u5c40\u6240\u5236\u5fa1\u306e\u5411\u4e0a\u304c\u751f\u5b58\u65e5\u6570\u306e\u5ef6\u9577\u306b\uff0c\u5fc5\u305a\u3057\u3082\u8ca2\u732e\u3059\u308b\u3068\u3082\u9650\u3089\u305a\uff0c\u751f\u5b58\u7387\u306e\u5411\u4e0a\u306e\u305f\u3081\u306b\u306f\u8ee2\u79fb\u6027\uff08\u5168\u8eab\u6027\uff09\u75be\u60a3\u306e\u5236\u5fa1\u3082\u5fc5\u8981\u3068\u306a\u308b\u304c2)<\/sup><\/strong>\uff0c\u3053\u306e\u305f\u3081\u306b\u306f\uff0c\u5c40\u6240\u6cbb\u7642\u306b\u5bfe\u3059\u308b\u5168\u8eab\u53cd\u5fdc\u306e\u8a98\u767a\u306b\u3088\u308a\u9054\u6210\u304c\u53ef\u80fd\u3068\u8003\u3048\u3089\u308c\uff0c\u5b9f\u969b\uff0c\u5c40\u6240\u52a0\u6e29\u306b\u3088\u308b\u514d\u75ab\u8abf\u7bc0\u52b9\u679c\u3084\uff0c\u6e29\u71b1\u4f75\u7528\u653e\u5c04\u7dda\u7167\u5c04\u306b\u3088\u308b\u30a2\u30d6\u30b9\u30b3\u30d1\u30eb\u52b9\u679c\u306b\u3064\u3044\u3066\u3082\u6307\u6458\u3055\u308c\u3066\u3044\u308b3)<\/sup><\/strong>\uff0e<\/p>\n\n\n\n \u81e8\u5e8a\u306b\u304a\u3051\u308b\u6e29\u71b1\u6cbb\u7642\u306e\u4e3b\u8981\u8ab2\u984c\u306e1\u3064\u306f\uff0c\u8133\u30fb\u4e2d\u67a2\u795e\u7d4c\u7cfb\u816b\u760d\u306b\u5bfe\u3059\u308b\u5b89\u5168\u306a\u9042\u884c\u3067\u3042\u308b\u304c\uff0cmEHT\u306f\uff0c\u8133\u816b\u760d\u306e\u6cbb\u7642\u6642\u306b\u304a\u3051\u308b\u5b89\u5168\u6027\u3068\uff0c\u518d\u767a\u6027\u8133\u816b\u760d\u306b\u5bfe\u3059\u308b\u7de9\u548c\u7684\u6cbb\u7642\u3068\u3057\u3066\u52a0\u6e29\u5358\u72ec\u3067\u6cbb\u7642\u3055\u308c\u305f\u969b\u306e\u6709\u7528\u6027\u3092\u793a\u3057\u305f\uff0e\u66f4\u306b\uff0c\u75be\u60a3\u304c\u5897\u60aa\u3059\u308b\u30ea\u30b9\u30af\u3082\u898b\u3089\u308c\u305a\uff0cmEHT\u3067\u6cbb\u7642\u3055\u308c\u305f\u60a3\u8005\u306e\u7121\u75c5\u751f\u5b58\u671f\u9593\u306e\u5ef6\u9577\u3082\u793a\u3055\u308c\u305f4)<\/sup><\/strong>\uff0eMinnaar\u3089\u306e\u5831\u544a\u306b\u3088\u308c\u3070\uff0c\u5bb9\u91cf\u52a0\u6e29\u6cd5(Capacitive heating)\u3067\u306f\uff0c\u6df1\u90e8\u816b\u760d\u306e\u52b9\u679c\u7684\u52a0\u71b1\u306f\u56f0\u96e3\u3068\u3055\u308c\u308b\u304c\uff0cmEHT\u3092\u7528\u3044\u308b\u3068\uff0c\u80a5\u6e80\u60a3\u8005\u3067\u3082\u6cbb\u7642\u52b9\u679c\u306e\u5411\u4e0a\u304c\u8a8d\u3081\u3089\u308c\uff0c\u6df1\u90e8\u9aa8\u76e4\uff08\u5b50\u5bae\u9838\u90e8\uff09\u816b\u760d\u306b\u5bfe\u3059\u308b\u6cbb\u7642\u6642\u3067\u3082\u5341\u5206\u306a\u5b89\u5168\u6027\u304c\u78ba\u4fdd\u3055\u308c\u308b\u3053\u3068\u304c\u7b2cIII\u76f8\u30e9\u30f3\u30c0\u30e0\u5316\u8a66\u9a13\u306b\u3088\u3063\u3066\u793a\u3055\u308c\u3066\u3044\u308b5)<\/sup><\/strong>\uff0e\u307e\u305f\uff0c\u5375\u5de3\u764c\uff0c\u80ba\u304a\u3088\u3073\u809d\u81d3\u3078\u306e\u6cbb\u7642\u5f8c\u306e\u518d\u767a\u60a3\u8005\u306e\u8179\u819c\u8ee2\u79fb\u306b\u5bfe\u3059\u308b\u7b2cI\/II\u76f8\u8a66\u9a13\u3067\u3082\uff0c\u7528\u91cf\u5236\u9650\u6bd2\u6027(dose limiting toxicities)\u306f\u8a8d\u3081\u3089\u308c\u305a\uff0c\u3053\u306e\u7814\u7a76\u3078\u306e\u53c2\u52a0\u8005\u306eBMI\u304c\uff0c\u6cbb\u7642\u52b9\u679c\u3068\u306f\u95a2\u9023\u3057\u306a\u304b\u3063\u305f\u3053\u3068\u304c\u793a\u3055\u308c\uff0c\u8102\u80aa\u5c64\u306e\u539a\u3055\u306b\u95a2\u308f\u3089\u305a\uff0cmEHT\u304c\u6df1\u90e8\u816b\u760d\u3092\u52b9\u679c\u7684\u306b\u52a0\u6e29\u3057\u5f97\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u305f\uff0e\u3055\u3089\u306b\uff0c\u524d\u81e8\u5e8a\u7814\u7a76\u3067\u6307\u6458\u3055\u308c\u305fmEHT\u306b\u3088\u308b\u514d\u75ab\u8abf\u7bc0\u52b9\u679c\u306b\u76f8\u5f53\u3059\u308b\u96fb\u96e2\u653e\u5c04\u7dda\u7167\u5c04\u6642\u306e\u30a2\u30d6\u30b9\u30b3\u30d1\u30eb\u5fdc\u7b54\u3082\u898b\u3089\u308c\u305f5)<\/sup><\/strong>\uff0e<\/p>\n\n\n\n \u306a\u304a\uff0c\u30d6\u30bf\u809d\u81d3\u3092\u7528\u3044\u305f\u52d5\u7269\u5b9f\u9a13\u7d50\u679c\u3067\u3082\uff0cmEHT\u306f\uff0c\u816b\u760d\u306e\u5341\u5206\u306a\u52a0\u71b1\u80fd\u529b\u3068\u816b\u760d\u5185\u8840\u6d41\u304a\u3088\u3073\u85ac\u7269\u5206\u5e03\u91cf\u306e\u6539\u5584\u52b9\u679c\u3092\u793a\u30576)<\/sup><\/strong>\uff0c\u764c\u6cbb\u7642\u6642\u306b\u4f75\u7528\u3055\u308c\u308b\u6e29\u71b1\u7642\u6cd5\u3068\u3057\u3066\uff0c\u6bd4\u8f03\u7684\u5bb9\u6613\u306b\u65bd\u884c\u53ef\u80fd\u3067\uff0c\u304b\u3064\u5b89\u5168\u3067\u52b9\u679c\u7684\u306b\u52a0\u6e29\u53ef\u80fd\u306a\u624b\u6cd5\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u308b\uff0e<\/p>\n\n\n\n \u3053\u308c\u3089\u306e\u5831\u544a\u306fmEHT\u3092\u7528\u3044\u305f\u57fa\u790e\u7814\u7a76\u304b\u3089\u81e8\u5e8a\u5fdc\u7528\u3055\u308c\u305f\u7d50\u679c\u307e\u3067\uff0c\u5e83\u7bc4\u306a\u5185\u5bb9\u3092\u542b\u3093\u3067\u3044\u308b\u304c\uff0c\u52a0\u6e29\u4e2d\u306e\u6e29\u5ea6\u6e2c\u5b9a\u304a\u3088\u3073\u6e29\u5ea6\u5206\u5e03\u306b\u95a2\u3059\u308b\u8a00\u53ca\u306f\u6b86\u3069\u306a\u304f\uff0c\u539f\u5247\uff0c\u51fa\u529b\u306e\u8abf\u6574\u306e\u307f\u3067mEHT\u306b\u3088\u308b\u52a0\u6e29\u304c\u9042\u884c\u3055\u308c\u305f\uff0e\u3053\u306e\u52a0\u6e29\u624b\u6cd5\u306f\uff0c\u826f\u597d\u306a\u816b\u760d\u52b9\u679c\u304c\u5f97\u3089\u308c\u305f\u969b\u306b\u521d\u3081\u3066\u6709\u7528\u6027\u304c\u8a8d\u3081\u3089\u308c\u308b\u624b\u6cd5\u3068\u3082\u8003\u3048\u3089\u308c\uff0c\u6cbb\u7642\u52b9\u679c\u306e\u5411\u4e0a\u306e\u305f\u3081\u306b\u306f\uff0c\u6cbb\u7642\u62c5\u5f53\u8005\u306emEHT\u3092\u7528\u3044\u305f\u52a0\u6e29\u7d4c\u9a13\u306b\u3082\u4f9d\u5b58\u3059\u308b\u3068\u601d\u308f\u308c\u308b\uff0e<\/p>\n\n\n\n \u53c2\u8003\u6587\u732e<\/strong><\/p>\n\n\n\n 1) Papp E, et al.<\/em> Energy absorption by the membrane rafts in the modulated electro-hyperthermia (mEHT). Open J Biophys 7: 216\u201329, 2017.<\/p>\n\n\n\n 2) Szasz AM, et al.<\/em><\/a> Review of the clinical evidences of modulated electro-hyperthermia (mEHT) method: An update for the practicing oncologist. Front Oncol 9: 1012, 2019.<\/p>\n\n\n\n 3) Datta NR, et al. <\/em>Local hyperthermia combined with radiotherapy and-\/or chemotherapy: recent advances and promises for the future. Cancer Treat Rev 41:742\u201353, 2015.<\/p>\n\n\n\n 4) Fiorentini G, et al.<\/em> Retrospective observational clinical study on relapsed malignant gliomas treated with electro-hyperthermia. Oncothermia J 22: 32\u201345, 2018.<\/p>\n\n\n\n 5) Minnaar CA, et al.<\/em> The effect of modulated electro-hyperthermia on local disease control in HIV-positive and -negative cervical cancer women in South Africa: early results from a phase III randomised controlled trial. PLoS ONE 14:e0217894, 2019.<\/p>\n\n\n\n 6) Balogh L, et al<\/em>. Temperature increase induced by modulated electrohyperthermia (oncothermia\u00ae<\/sup>) in the anesthetized pig liver. J Cancer Res Ther 12: 1153\u20139, 2016.<\/p>\n\n\n\n \u7528\u8a9e\u89e3\u8aac<\/strong><\/p>\n\n\n\n \u30aa\u30f3\u30b3\u30b5\u30fc\u30df\u30a2\uff0c<\/strong>Modulated Electro Hyperthermia (mEHT<\/strong>\uff09\uff1a<\/strong><\/p>\n\n\n\n mEHT\u306f\u632f\u5e45\u5909\u8abf\u3057\u305f13.56 MHz\u30e9\u30b8\u30aa\u6ce2(RF)\u3092\u7528\u3044\u305f\u5bb9\u91cf\u7d50\u5408\u578b\u52a0\u6e29\u6cd5\u3067\u3042\u308b\uff0e\u6e29\u5ea6\u4e0a\u6607\u3092\u6cbb\u7642\u306b\u5229\u7528\u3059\u308b\u3068\u3082\u306b\u96fb\u78c1\u6ce2\u306e\u3044\u308f\u3086\u308b\u975e\u71b1\u7684\u4f5c\u7528\u3092\u6cbb\u7642\u306b\u751f\u304b\u3059\u3079\u304f\uff0c\u816b\u760d\u7d30\u80de\u819c\u306b\u9023\u7d9a\u7684\u306a\u6e29\u5ea6\u52fe\u914d\u3092\u751f\u3058\u3055\u305b\u308b\u7b49\u306e\u7279\u9577\u3092\u6709\u3059\u308b\uff0e\u51fa\u529b\u306f\u6700\u5927150 W\u3067\u816b\u760d\u5185\u6e29\u5ea6\u306f\u3044\u308f\u3086\u308b\u201c\u30de\u30a4\u30eb\u30c9\u30cf\u30a4\u30d1\u30fc\u30b5\u30df\u30a2\u201d\u6c34\u6e96\u306e<42o<\/sup>C\u3067\u3042\u308b\uff0e\u307e\u305f\u4f4e\u51fa\u529b\u306eRF\u3092\u7528\u3044\u308b\u305f\u3081\uff0c\u8a2d\u7f6e\u306b\u3042\u305f\u3063\u3066\u306f\u30b7\u30fc\u30eb\u30c9\u30eb\u30fc\u30e0\u3092\u5fc5\u8981\u3068\u305b\u305a\uff0c\u706b\u50b7\u7b49\u306e\u526f\u4f5c\u7528\u3082\u5c11\u306a\u3044\u3068\u3055\u308c\u308b\uff0e\u6b27\u5dde\u3084\u30a2\u30b8\u30a2\u3092\u4e2d\u5fc3\u306b\u666e\u53ca\u3057\u3066\u3044\u308b\uff0e\u8a73\u7d30\u306fSzasz A, Szasz N, Szasz O.: Onocthermia: Principles and Practices.<\/a> Springer, 2011\u306e\u53e2\u66f8\u306b\u8a18\u8f09\u3055\u308c\u3066\u3044\u308b\uff0e<\/p>\n","protected":false},"excerpt":{"rendered":" \u4e00\u793e\uff09\u65e5\u672c\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\u5b66\u4f1a\u30cb\u30e5\u30fc\u30b9No.111\u3010\u5b66\u8853\u5831\u544a46\u3011\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\u306b\u95a2\u3059\u308b\u6700\u8fd1\u306e\u8a71\u984c46 \u201c\u30aa\u30f3\u30b3\u30b5\u30fc\u30df\u30a2\u201d\uff08Modulated Electro Hyperthermia [mEHT])\u306e\u81e8\u5e8a […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"vkexunit_cta_each_option":"","footnotes":""},"categories":[5],"tags":[],"class_list":["post-538","post","type-post","status-publish","format-standard","hentry","category-report"],"_links":{"self":[{"href":"https:\/\/idsc-gunma.jp\/congress\/jstm\/wp-json\/wp\/v2\/posts\/538","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idsc-gunma.jp\/congress\/jstm\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idsc-gunma.jp\/congress\/jstm\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idsc-gunma.jp\/congress\/jstm\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/idsc-gunma.jp\/congress\/jstm\/wp-json\/wp\/v2\/comments?post=538"}],"version-history":[{"count":1,"href":"https:\/\/idsc-gunma.jp\/congress\/jstm\/wp-json\/wp\/v2\/posts\/538\/revisions"}],"predecessor-version":[{"id":539,"href":"https:\/\/idsc-gunma.jp\/congress\/jstm\/wp-json\/wp\/v2\/posts\/538\/revisions\/539"}],"wp:attachment":[{"href":"https:\/\/idsc-gunma.jp\/congress\/jstm\/wp-json\/wp\/v2\/media?parent=538"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idsc-gunma.jp\/congress\/jstm\/wp-json\/wp\/v2\/categories?post=538"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idsc-gunma.jp\/congress\/jstm\/wp-json\/wp\/v2\/tags?post=538"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}