{"id":552,"date":"2020-02-06T20:28:00","date_gmt":"2020-02-06T11:28:00","guid":{"rendered":"https:\/\/idsc-gunma.jp\/congress\/jstm\/?p=552"},"modified":"2022-05-26T20:24:10","modified_gmt":"2022-05-26T11:24:10","slug":"%e8%bf%91%e8%b5%a4%e5%a4%96%e5%85%89%e7%85%a7%e5%b0%84%e3%81%ab%e3%82%88%e3%82%8b%e7%a3%81%e6%80%a7%e3%83%8a%e3%83%8e%e7%b2%92%e5%ad%90%e3%81%ae%e5%8a%a0%e6%b8%a9%e3%81%a8%e3%83%8f%e3%82%a4%e3%83%91","status":"publish","type":"post","link":"https:\/\/idsc-gunma.jp\/congress\/jstm\/%e8%bf%91%e8%b5%a4%e5%a4%96%e5%85%89%e7%85%a7%e5%b0%84%e3%81%ab%e3%82%88%e3%82%8b%e7%a3%81%e6%80%a7%e3%83%8a%e3%83%8e%e7%b2%92%e5%ad%90%e3%81%ae%e5%8a%a0%e6%b8%a9%e3%81%a8%e3%83%8f%e3%82%a4%e3%83%91\/","title":{"rendered":"\u8fd1\u8d64\u5916\u5149\u7167\u5c04\u306b\u3088\u308b\u78c1\u6027\u30ca\u30ce\u7c92\u5b50\u306e\u52a0\u6e29\u3068\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\u3078\u306e\u5fdc\u7528"},"content":{"rendered":"\n<p>\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\u306b\u95a2\u3059\u308b\u6700\u8fd1\u306e\u8a71\u984c39<\/p>\n\n\n\n<p>\u8fd1\u8d64\u5916\u5149\u7167\u5c04\u306b\u3088\u308b\u78c1\u6027\u30ca\u30ce\u7c92\u5b50\u306e\u52a0\u6e29\u3068\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\u3078\u306e\u5fdc\u7528<\/p>\n\n\n\n<p>\u4e95\u85e4\u3000\u5f70\uff08\u540d\u53e4\u5c4b\u5927\u5b66 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nm\uff080.25 W\/cm<sup>2<\/sup>\uff09\u306e\u30ec\u30fc\u30b6\u30fc\u3092\u4f7f\u7528\u3057\u3066\uff0c0.8 mg\/mL\u306e\u30de\u30b0\u30cd\u30bf\u30a4\u30c8\uff08\u7c92\u5b50\u5f84\u7d0410 nm\uff09\u3092\u7167\u5c04\u3057\u305f\u3068\u3053\u308d\uff0c20\u5206\u9593\u306725\u2103\u306e\u767a\u71b1\u304c\u5f97\u3089\u308c\u305f\u3053\u3068\u3092\u5831\u544a\u3057\u305f<sup>3)<\/sup>\uff0e \u3053\u306e\u52a0\u6e29\u306b\u3088\u308a\uff0c<em>in vitro<\/em>\u306b\u304a\u3051\u308b\u691c\u8a0e\u3067\u30d2\u30c8\u98df\u9053\u304c\u3093\u7d30\u80de\u682aEca-109\u306e\u751f\u7d30\u80de\u7387\u309240\uff05\u306b\u6e1b\u5c11\u3055\u305b\u305f\uff0e\u3055\u3089\u306b\uff0c<em>in vivo<\/em>\u306b\u304a\u3051\u308b\u691c\u8a0e\u3067\u62c5\u764c\u30de\u30a6\u30b9\u306e\u816b\u760d\u5897\u6b96\u309224\u65e5\u9593\u306b\u308f\u305f\u3063\u3066\u6291\u5236\u3057\u305f\uff0e<\/p>\n\n\n\n<p>\u30de\u30b0\u30cd\u30bf\u30a4\u30c8\u306e\u78c1\u5834\u8a98\u5c0e\u52a0\u6e29\u306b\u3088\u308b\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\u30b7\u30b9\u30c6\u30e0\u306f\uff0c\u78c1\u5834\u7167\u5c04\u88c5\u7f6e\u306e\u958b\u767a\u304c\u5b9f\u7528\u5316\u3078\u306e\u30dc\u30c8\u30eb\u30cd\u30c3\u30af\u306b\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\uff0e\u4e00\u65b9\uff0c\u8fd1\u8d64\u5916\u5149\u306e\u7167\u5c04\u88c5\u7f6e\u306f\u958b\u767a\u304c\u6bd4\u8f03\u7684\u5bb9\u6613\u3067\u3042\u308a\uff0c\u6a5f\u5668\u81ea\u4f53\u306e\u4fa1\u683c\u3082\u4f4e\u304f\u6291\u3048\u3089\u308c\u308b\u5229\u70b9\u304c\u3042\u308b\uff0e\u3057\u304b\u3057\uff0c\u78c1\u5834\u304c\u4f53\u5185\u3092\u900f\u904e\u3057\u3084\u3059\u3044\u306e\u306b\u5bfe\u3057\u3066\uff0c\u8fd1\u8d64\u5916\u5149\u306e\u7167\u5c04\u306b\u3088\u3063\u3066\u900f\u904e\u3059\u308b\u306e\u306f\u4f53\u8868\u9762\u304b\u3089\u6570\u30df\u30ea\u30e1\u30fc\u30c8\u30eb\u3067\u3042\u308b\u3068\u3055\u308c\u308b\u304c\uff0c\u7c73\u56fd\u7acb\u304c\u3093\u7814\u7a76\u6240\u306e\u5c0f\u6797\u4e45\u9686\u535a\u58eb\u304c\u958b\u767a\u3057\u305f\u8fd1\u8d64\u5916\u5149\u7dda\u514d\u75ab\u6cbb\u7642\u6cd5\u306b\u304a\u3044\u3066\u3082\uff0c\u6df1\u90e8\u764c\u306b\u5bfe\u3057\u3066\u306f\u5185\u8996\u93e1\u3092\u4f7f\u7528\u3055\u308c\u308b\u3053\u3068\u304b\u3089\uff0c\u8fd1\u8d64\u5916\u5149\u3092\u7528\u3044\u305f\u30ec\u30fc\u30b6\u30fc\u88c5\u7f6e\u306e\u958b\u767a\u306f\u52a0\u901f\u3055\u308c\u308b\u3067\u3042\u308d\u3046\uff0e<\/p>\n\n\n\n<p>\u30ca\u30ce\u7c92\u5b50\u3092\u7528\u3044\u308b\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\u306b\u304a\u3051\u308b\u3082\u3046\u4e00\u3064\u306e\u30dc\u30c8\u30eb\u30cd\u30c3\u30af\u306f\uff0c\u85ac\u7269\u9001\u9054\u30b7\u30b9\u30c6\u30e0\u3067\u3042\u308b\uff0e\u3064\u307e\u308a\uff0c\u6cbb\u7642\u306e\u305f\u3081\u306e\u767a\u71b1\u306b\u5341\u5206\u306a\u30ca\u30ce\u7c92\u5b50\u3092\u816b\u760d\u306b\u9001\u9054\u3059\u308b\u3053\u3068\u304c\u56f0\u96e3\u3067\u3042\u308b\uff0e\u6700\u8fd1Guo\u3089\u306f\uff0c\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u96c6\u7a4d\u6027\u306e\u3042\u308b\u8102\u6eb6\u6027\u30ab\u30c1\u30aa\u30f3\uff08Triphenylphosphonium cation, TPP\uff09\u3067\u8868\u9762\u4fee\u98fe\u3057\u305f\u30de\u30b0\u30cd\u30bf\u30a4\u30c8\u3092\u7528\u3044\u308b\u3053\u3068\u3067\uff0c\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a19\u7684\u578b\u306e\u30de\u30b0\u30cd\u30bf\u30a4\u30c8\u3092\u958b\u767a\u3057\uff0c\u8fd1\u8d64\u5916\u5149\u3067\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3092\u52a0\u6e29\u3059\u308b\u30b7\u30b9\u30c6\u30e0\u306b\u3064\u3044\u3066\u5831\u544a\u3057\u305f<sup>4)<\/sup>\uff0e\u3053\u306e\u3088\u3046\u306a\u300c\u30ac\u30f3\u306e\u6025\u6240\u3092\u653b\u6483\u3059\u308b\u30ca\u30ce\u30d2\u30fc\u30bf\u30fc\u300d\u3092\u7528\u3044\u308b\u3053\u3068\u3067\uff0c\u816b\u760d\u306b\u9001\u9054\u3055\u308c\u308b\u30ca\u30ce\u7c92\u5b50\u304c\u5c11\u91cf\u3067\u3042\u3063\u3066\u3082\u9ad8\u3044\u6cbb\u7642\u52b9\u679c\u3092\u793a\u3059\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\u304c\u53ef\u80fd\u306b\u306a\u308b\u304b\u3082\u3057\u308c\u306a\u3044\uff0e<\/p>\n\n\n\n<p>\u53c2\u8003\u6587\u732e\uff1a<\/p>\n\n\n\n<p>1)&nbsp; Ito A.,&nbsp;<em>et al<\/em>. Intracellular hyperthermia using magnetic nanoparticles: A novel method for hyperthermia clinical applications. Thermal Med, 24: 113-29, 2008.<\/p>\n\n\n\n<p>2)&nbsp; De Matteis V.,&nbsp;<em>et al<\/em>. Engineered gold nanoshells killing tumor cells: New perspectives. Curr Pharm Des, 25: 1477-89, 2019.<\/p>\n\n\n\n<p>3)&nbsp; Chu M.,&nbsp;<em>et al<\/em>. Near-infrared laser light mediated cancer therapy by photothermal effect of Fe<sub>3<\/sub>O<sub>4<\/sub>&nbsp;magnetic nanoparticles. Biomaterials, 34: 4078-88, 2013.<\/p>\n\n\n\n<p>4)&nbsp; Guo R.,&nbsp;<em>et al<\/em>. Mitochondria-targeting magnetic composite nanoparticles for enhanced phototherapy of cancer. Small, 12: 4541-52, 2016.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\u306b\u95a2\u3059\u308b\u6700\u8fd1\u306e\u8a71\u984c39 \u8fd1\u8d64\u5916\u5149\u7167\u5c04\u306b\u3088\u308b\u78c1\u6027\u30ca\u30ce\u7c92\u5b50\u306e\u52a0\u6e29\u3068\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\u3078\u306e\u5fdc\u7528 \u4e95\u85e4\u3000\u5f70\uff08\u540d\u53e4\u5c4b\u5927\u5b66 \u5927\u5b66\u9662\u5de5\u5b66\u7814\u7a76\u79d1 \u5316\u5b66\u30b7\u30b9\u30c6\u30e0\u5de5\u5b66\u5c02\u653b\uff09 \u30de\u30b0\u30cd\u30bf\u30a4\u30c8\uff08Fe3O4\uff09\u304b\u3089\u306a\u308b\u78c1\u6027\u30ca\u30ce\u7c92\u5b50\u306f\u9ad8\u5468 [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"vkexunit_cta_each_option":"","footnotes":""},"categories":[5],"tags":[],"class_list":["post-552","post","type-post","status-publish","format-standard","hentry","category-report"],"_links":{"self":[{"href":"https:\/\/idsc-gunma.jp\/congress\/jstm\/wp-json\/wp\/v2\/posts\/552","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/idsc-gunma.jp\/congress\/jstm\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/idsc-gunma.jp\/congress\/jstm\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/idsc-gunma.jp\/congress\/jstm\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/idsc-gunma.jp\/congress\/jstm\/wp-json\/wp\/v2\/comments?post=552"}],"version-history":[{"count":1,"href":"https:\/\/idsc-gunma.jp\/congress\/jstm\/wp-json\/wp\/v2\/posts\/552\/revisions"}],"predecessor-version":[{"id":553,"href":"https:\/\/idsc-gunma.jp\/congress\/jstm\/wp-json\/wp\/v2\/posts\/552\/revisions\/553"}],"wp:attachment":[{"href":"https:\/\/idsc-gunma.jp\/congress\/jstm\/wp-json\/wp\/v2\/media?parent=552"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/idsc-gunma.jp\/congress\/jstm\/wp-json\/wp\/v2\/categories?post=552"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/idsc-gunma.jp\/congress\/jstm\/wp-json\/wp\/v2\/tags?post=552"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}